Toxicology Track

Weekly Newsletter of the MSU Center for Integrative Toxicology
Director: Norbert Kaminski/Editor: Lois Furry

June 12, 2007, Vol. 30, Number 23

Seminars / Publications / Grants / Workshops/

Seminars

The National Food Safety and Toxicology Center presents Melvin Bernstein, Vice President for Research, University of Maryland, to give the Robert Leader Endowed Lecture on Wednesday, June 13, 2007 at 4 p.m. in Beg Ten Room B, Kellogg Center.

*The Center for Integrative Toxicology and the Department of Food Science and Human Nutrition present Marina Guizzetti, Ph.D., Department of Environmental and Occupational Health Sciences, University of Washington, to speak on "Brain Cholesterol Homeostasis as a Target for the Developmental Neurotoxicity of Ethanol" on Monday, June 18, 2007 at 12 noon in 206 G.M. Trout Building.  Dr. Guizzetti is a candidate for the CIT's faculty position in chemical carcinogenesis or developmental toxicology. 

*The Center for Integrative Toxicology and the Department of Pharmacology and Toxicology present Helen Sable, Ph.D., Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign, to speak on "PCBs and Inhibitory Control: Implications for Neuropsychiatric Conditions" on Wednesday, June 20, 2007 at 12 noon in B448-9 Life Sciences Building.  Dr. Sable is a candidate for the CIT's faculty position in chemical carcinogenesis or developmental toxicology. 

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs.  Seminars that fulfill this requirement are archived at seminars.

Publications

Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine. Deng X, Luyendyk JP, Zou W, Lu J, Malle E, Ganey PE, Roth RA. J Pharmacol Exp Ther. 2007 May 15; [Epub ahead of print]

Evaluation of effects from repeated inhalation exposure of f344 rats to high concentrations of propylene. Pottenger LH, Malley LA, Bogdanffy MS, Donner EM, Upton PB, Li Y, Walker VE, Harkema JR, Banton MI, Swenberg JA. Toxicol Sci. 2007 Jun;97(2):336-47.

Neurotoxicity and Inflammation in the Nasal Airways of Mice Exposed to the Macrocyclic Trichothecene Mycotoxin Roridin A: Kinetics and Potentiation by Bacterial Lipopolysaccharide Co-Exposure. Islam Z, Amuzie CJ, Harkema JR, Pestka JJ. Toxicol Sci. 2007 May 4; [Epub ahead of print].

Virulence factor activity relationships: challenges and development approaches. Tourlousse DM, Stedtfeld RD, Baushke SW, Wick LM, Hashsham SA. Water Environ Res. 2007 Mar;79(3):246-59. Review.

Multiplex approach for screening genetic markers of microbial indicators. Stedtfeld RD, Baushke S, Tourlousse D, Chai B, Cole JR, Hashsham SA. Water Environ Res. 2007 Mar;79(3):260-9.

Time-Dependent Airway Epithelial and Inflammatory Cell Responses Induced by Influenza Virus A/PR/8/34 in C57BL/6 Mice. Buchweitz JP, Harkema JR, Kaminski NE. Toxicol Pathol. 2007;35(3):424-35.

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC, Clarkson TW, Cook RR, Diamond DM, Doolittle DJ, Dorato MA, Duke SO, Feinendegen L, Gardner DE, Hart RW, Hastings KL, Hayes AW, Hoffmann GR, Ives JA, Jaworowski Z, Johnson TE, Jonas WB, Kaminski NE, Keller JG, Klaunig JE, Knudsen TB, Kozumbo WJ, Lettieri T, Liu SZ, Maisseu A, Maynard KI, Masoro EJ, McClellan RO, Mehendale HM, Mothersill C, Newlin DB, Nigg HN, Oehme FW, Phalen RF, Philbert MA, Rattan SI, Riviere JE, Rodricks J, Sapolsky RM, Scott BR, Seymour C, Sinclair DA, Smith-Sonneborn J, Snow ET, Spear L, Stevenson DE, Thomas Y, Tubiana M, Williams GM, Mattson MP. Toxicol Appl Pharmacol. 2007 Mar 7; [Epub ahead of print].

Methylene blue dye test for rapid qualitative detection of hydroxyl radicals formed in a Fenton's reaction aqueous solution. Satoh AY, Trosko JE, Masten SJ. Environ Sci Technol. 2007 Apr 15;41(8):2881-7.

Genes and respiratory disease: a first step on a long journey. Ewart SL, Robinson NE. Equine Vet J. 2007 May;39(3):270-4.

Histological evaluation of the equine larynx after unilateral laser-assisted ventriculocordectomy. Robinson P, Williams KJ, Sullins KE, Arnoczky SP, Stick JA, Robinson NE, de Feijter-Rupp H, Derksen FJ. Equine Vet J. 2007 May;39(3):222-5.

Trimetoquinol: bronchodilator effects in horses with heaves following aerosolised and oral administration. Camargo FC, Robinson NE, Berney C, Eberhart S, Baker S, Detolve P, Derksen FJ, Lehner AF, Hughes C, Tobin T. Equine Vet J. 2007 May;39(3):215-20.

Variations in worker compensation claims by company-the potential for achieving a significant reduction in claims. Rosenman KD, Kalush A, Reilly MJ. Am J Ind Med. 2007 Jun;50(6):415-20.

Investigating asthma deaths among children and young adults: Michigan Asthma Mortality Review. Rosenman KD, Hanna EA, Lyon-Callo SK, Wasilevich EA. Public Health Rep. 2007 May-Jun;122(3):373-81.

Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. Song W, Huang M, Rumbeiha W, Li H. Rapid Commun Mass Spectrom. 2007 May 17;21(12):1944-1950 [Epub ahead of print].

Determination of endogenous norepinephrine levels in different chambers of the rat heart by capillary electrophoresis coupled with amperometric detection. Novotny M, Quaiserova-Mocko V, Wehrwein EA, Kreulen DL, Swain GM. J Neurosci Methods. 2007 Jun 15;163(1):52-9.

Microbial populations in antarctic permafrost: biodiversity, state, age, and implication for astrobiology. Gilichinsky DA, Wilson GS, Friedmann EI, McKay CP, Sletten RS, Rivkina EM, Vishnivetskaya TA, Erokhina LG, Ivanushkina NE, Kochkina GA, Shcherbakova VA, Soina VS, Spirina EV, Vorobyova EA, Fyodorov-Davydov DG, Hallet B, Ozerskaya SM, Sorokovikov VA, Laurinavichyus KS, Shatilovich AV, Chanton JP, Ostroumov VE, Tiedje JM. Astrobiology. 2007 May;7(2):275-311.

Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis. Hirabayashi Y, Yoon BI, Tsuboi I, Huo Y, Kodama Y, Kanno J, Ott T, Trosko JE, Inoue T. Exp Biol Med (Maywood). 2007 May;232(5):700-12.

Grants

Steven Bursian received $20,000 from the Fur Commission USA for “Research on Nutrition; Toxicology Behavior and Management of Mink.”

Jack Harkema received $3,703 from the University of Rochester for research.

Workshops

The MSU CIT Superfund Program, Research Translation Core, is hosting a one-day workshop on September 19, 2007 at the MSU Kellogg Center to review and exchange ideas concerning the findings of the recently releases studies by the National Academy of Science and the World Health Organization on dioxin and dioxin-like compounds, and how these findings may be used in formulating national and international environmental policies and regulations. As part of the Superfund Basic Research Program grant to MSU from the National Institute of Environmental Health Science, this workshop is being provided free-of-charge to all participants, but seating capacity is limited.  Ensure your place by calling 517-353-6469 or e-mailing tox@msu.edu as soon as possible.  Overnight accommodations are available at the Kellogg Center by calling 517-432-4000.  The registration brochure is attached.

CSTAT is pleased to announce the second set of workshops in the Summer 2007 Workshop Series. For more information and registration please visit our website. http://www.cstat.msu.edu/workshops.html

Statistics Refresher, Tuesday, June 5, from 1-4 PM
Dr. Kimberly Maier, CEPSE and Dr. Connie Page, Statistics and Probability

Introduction to Bayesian Statistics, Thursday, June 7, from 1-4 PM
Dr. Sarat Dass, Statistics and Probability

Basic Data Analysis using SPSS, Friday, June 15, 1-4 PM
Dr. Sandra Herman, CSTAT

Basic Data Analysis using STATA, Friday, June 22, from 1-4 PM
Dr. Freda Lynn, Education

Intermediate Data Analysis using SPSS, Friday, July 13, 1-4 PM
Dr. Sandra Herman, CSTAT