Toxicology Track

Weekly Newsletter of the MSU Center for Integrative Toxicology
Director: Norbert Kaminski/Editor: Lois Furry

October 15, 2007, Vol. 30, Number 37

Seminars this week/Seminars upcoming/Publications/Conferences

Seminars this week

The Cell and Molecular Biology Program research forum with Laura Lamb speaking on "Survival Signaling in Prostate Cancer Cells Expressing Androgen Receptor" will be held on Tuesday, October 16, 2007 at 1 p.m. in 2245 Biomedical Physical Sciences.

The Department of Microbiology and Molecular Genetics presents Tim Read, Naval Medical Research Center, to speak on "New Sequencing Technologies, Biothreat Agent Detection and the Pathogen Population Genomics Landscape" on Tuesday, October 16, 2007 at 4:10 p.m. in 1415 Biomedical Physical Sciences.

*The Departments of Chemistry and of Environmental Engineering present Jerome Rose, PH.S, European Center for Educational and Research in Environmental Geosciences, to speak on “Transfer, Reactivity, and Toxicity of Inorganic Contaminants: A Molecular Scale Approach Developed at the CEREGE (Aix, France)” on Wednesday, October 17, 2007 at 4:10 p.m. in 136 Chemistry.

The Biochemistry and Molecular Biology Department presents Dan Ray, University of California- LA, to speak on "Post-transcriptional Regulation of S-phase Expressed Genes in Kinetopastids by Sequence-Specific RNA-binding" on Thursday, October 18, 2007 at 11:30 a.m. in 101 Biochemistry.

The Department of Physiology presents Fred Lamb, Division Head, Pediatric Critical Care, Medical Director, Pediatric Intensive Care Unit, University of Iowa, who will speak on "Cytokine-Induced Reactive Oxygen Signaling Occurs in Early Endosomes and Requires Nox 1 and the CIC-3 Anion Exchanger" on Thursday, October 18, 2007 at 4 p.m. in 1425 Biomedical Physical Sciences.

A Chemical Engineering and Materials Science seminar by Michael Paulaitis, Ohio State University on "Cellular Microarrays to Characterize Immune Response" will take place on Friday, October 19, 2007 at 11:30 a.m. in 1400 Biomedical Physical Sciences.

The Respiratory Research Initiative presents James Wagner, MSU, to speak on "Complementary and Alternative Therapies for Allergic Airway Diseases: Update and Potential New Proposals" on Friday, October 19, 2007 at 11:30 a.m. in A214 CVM, Buchanan Room.

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs.  Seminars that fulfill this requirement are archived at http://www.cit.msu.edu/Graduate%20Program/seminars.html.

Seminars upcoming

The Graduate School Hans Kende Memorial Lecture Series on Integrity and Mentoring in Research presents Dr. Paul Friedman, professor emeritus of radiology, University of California, San Diego to speak on "An Introduction to Integrity in Research" on Wednesday, October 24, 2007 at 3:30 p.m. in Big Ten B, Kellogg Center. Reception to follow. Please register via email to gradwrsp@msu.edu. Include your name, department, email address, and the name of the lecture.

The Biochemistry and Molecular Biology Program presents Jim Imlay, University of Illinois, to give the Wells Lectureship on "Molecular Explanations for the Toxicity of Oxygen" on Thursday, October 25, 2007 at 11:30 a.m. in 101 Biochemistry.

The CIT is hosting a lecture by Albert E. Munson, director of the Health Effects Laboratory Division for the National Institute of Occupational Safety and Health, entitled "Toxicology in an Occupational Government Laboratory" at noon on Thursday, November 8, 2007 at the Holden Hall Hunt Club. Lunch is included. Reservations required at tox@msu.edu.

Publications

Beckett KJ, Yamini B, Bursian SJ. The Effects of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) on Mink (Mustela vison) Reproduction and Kit Survivability and Growth. Arch Environ Contam Toxicol. 2007 Aug 3; [Epub ahead of print]

Li X, Fleis RI, Shubitowski DM, Ramadas RA, Ewart SL. Fine mapping of murine asthma quantitative trait loci and analyses of Ptgs1 and Mrc1 as positional candidate genes. DNA Seq. 2007 Jun;18(3):190-5.

Shaw PJ, Hopfensperger MJ, Ganey PE, Roth RA. Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha. Toxicol Sci. 2007 Aug 19; [Epub ahead of print]

Tukov FF, Luyendyk JP, Ganey PE, Roth RA. The Role of Tumor Necrosis Factor alpha in Lipopolysaccharide/Ranitidine-induced Inflammatory Liver Injury. Toxicol Sci. 2007 Aug 13; [Epub ahead of print]

Deng X, Luyendyk JP, Zou W, Lu J, Malle E, Ganey PE, Roth RA. Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine. J Pharmacol Exp Ther. 2007 Aug;322(2):852-61. Epub 2007 May 15.

Thomas J, Haseman JK, Goodman JI, Ward JM, Loughran TP Jr, Spencer PJ. A review of large granular lymphocytic leukemia in Fischer 344 rats as an initial step toward evaluating the implication of the endpoint to human cancer risk assessment. Toxicol Sci. 2007 Sep;99(1):3-19. Epub 2007 May 22. Review.

Behrouz B, Drolet RE, Sayed ZA, Lookingland KJ, Goudreau JL. Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult. Neuroscience. 2007 Jul 13;147(3):592-8. Epub 2007 Jun 20.

Wagner JG, Jiang Q, Harkema JR, Illek B, Patel DD, Ames BN, Peden DB. Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol. Free Radic Biol Med. 2007 Oct 15;43(8):1176-88. Epub 2007 Jul 20.

Rodriguez TE, Falkowski NR, Harkema JR, Huffnagle GB.Analysis of the Role of Neutrophils in Preventing and Resolving Acute Fungal Sinusitis. Infect Immun. 2007 Sep 17; [Epub ahead of print]

Buchweitz JP, Karmaus PW, Harkema JR, Williams KJ, Kaminski NE. Modulation Of Airway Responses To Influenza A/PR/8/34 By Delta-9-Tetrahydrocannabinol In C57BL/6 Mice. J Pharmacol Exp Ther. 2007 Aug 28; [Epub ahead of print]

Miller R, Kaneene JB, Schmitt SM, Lusch DP, Fitzgerald SD. Spatial analysis of Mycobacterium bovis infection in white-tailed deer (Odocoileus virginianus) in Michigan, USA. Prev Vet Med. 2007 Nov 15;82(1-2):111-22. Epub 2007 Jun 26.

Rose LV, Arthur AE, Hong SY, Chanda A, Linz JE. The initiation and pattern of spread of histone H4 acetylation parallel the order of transcriptional activation of genes in the aflatoxin cluster. Mol Microbiol. 2007 Oct 5; [Epub ahead of print]

Rose LV, Beaudry RM, Arthur AE, Calvo, AM, Linz JE. Aspergillus Volatiles Regulate Aflatoxin Synthesis and Asexual Sporulation in Aspergillus parasiticus. Appl Environ Microbiol. 2007 Sep 21; [Epub ahead of print]

Parsons MJ, Long DT, Yohn SS, Giesy JP. Spatial and temporal trends of mercury loadings to Michigan inland lakes. Environ Sci Technol. 2007 Aug 15;41(16):5634-40.

Li X, Hupp AM, McGuffin VL. The thermodynamic and kinetic basis of liquid chromatography. Adv Chromatogr. 2007;45:1-88.

Gray JS, Pestka JJ.Transcriptional regulation of deoxynivalenol-induced IL-8 expression in human monocytes. Toxicol Sci. 2007 Oct;99(2):502-11. Epub 2007 Jul 16.

Xue L, Pestka JJ, Li M, Firestone GL, Bjeldanes LF. 3,3'-Diindolylmethane stimulates murine immune function in vitro and in vivo. J Nutr Biochem. 2007 Aug 16; [Epub ahead of print]

Holcombe SJ, Derksen FJ, Robinson NE. Electromyographic activity of the palatinus and palatopharyngeus muscles in exercising horses. Equine Vet J. 2007 Sep;39(5):451-5.

Derksen FJ, Williams KJ, Uhal BD, Slocombe RF, de Feijter-Rupp H, Eberhart S, Berney C, Robinson NE. Pulmonary response to airway instillation of autologous blood in horses. Equine Vet J. 2007 Jul;39(4):334-9.

Rosenman KD. Clean as a Whistle, But What about that Wheeze? Am J Respir Crit Care Med. 2007 Oct 15;176(8):731-2.

Dai Y, Proshlyakov DA, Zak JK, Swain GM. Optically Transparent Diamond Electrode for Use in IR Transmission Spectroelectrochemical Measurements. Anal Chem. 2007 Oct 1;79(19):7526-7533. Epub 2007 Sep 5.

Park J, Galligan JJ, Fink GD, Swain GM. Differences in Sympathetic Neuroeffector Transmission to Rat Mesenteric Arteries and Veins as Probed by In Vitro Continuous Amperometry and Video Imaging. J Physiol. 2007 Sep 6; [Epub ahead of print]

Hansen AA, Herbert RA, Mikkelsen K, Jensen LL, Kristoffersen T, Tiedje JM, Lomstein BA, Finster KW. Viability, diversity and composition of the bacterial community in a high Arctic permafrost soil from Spitsbergen, Northern Norway. Environ Microbiol. 2007 Nov;9(11):2870-84.

Konstantinidis KT, Tiedje JM. Prokaryotic taxonomy and phylogeny in the genomic era: advancements and challenges ahead. Curr Opin Microbiol. 2007 Oct 6; [Epub ahead of print]

Smith DJ, Park J, Tiedje JM, Mohn WW. A large gene cluster in Burkholderia xenovorans encoding abietane diterpenoid catabolism. J Bacteriol. 2007 Sep;189(17):6195-204. Epub 2007 Jun 22.

Yang C, Klein, EA, Assoian, RK and Kazanietz, MG. Heregulin promotes breast cancer cell proliferation via Rac/Erk-dependent induction of cyclin D1 and p21cip1. Biochem. J. (in press) 2007.

Conferences and other events

Students in the Environmental and Integrative Toxicological Sciences program are reminded of the requirement for training in research ethics offered by the University. Specific information and a complete description of all the sessions in the Responsible Conduct of Research Seminar Series is available at the series' web site: http://grad.msu.edu/all/respconduct.htm

The Graduate School is holding a Graduate Student Reception on Thursday, October 18, 2007 from 4:30 to 6:30 p.m. in Big Ten Room C, Kellogg Center. This is an opportunity to network and meet with graduate student organization leaders, faculty, and administrators. $100 drawings and prizes for graduate students. RSVP to gradwrsp@gmail.com or call 353-3262.

Waters Corporation will hold a Bioseparations Seminar on Wednesday, October 24, 2007 from 8 a.m. to noon in 1425 Biomedical Sciences Building. This educational seminar will introduce you to new Waters technologies specifically developed for biomolecule analysis and isolation. LC/MS sample preparation platforms, UltraPerformance LC® , High Definition MS™, FDA CGMP compliance, and isolation strategies will be addressed. Register at www.waters.com/seminars.

The University of Michigan Center for Risk Science and Communication presents the 2007 Bernstein Symposium: Nanotechnology and Health: Evidence and Impact on October 25-26, 2007 at the Biomedical Science Research Building (BSRB) 109 Zina Pitcher, Ann Arbor, Michigan. The Center, under the leadership of Dr. Martin Philbert, has put together a program that will bring together leading scientists and policymakers to examine the emerging field of nanotechnology, its potential impact on human health, and the growing debate over whether and how to regulate nanotechnology products. A broad array of expert speakers will present including Christine Todd Whitman, former MI U.S. Rep. Joe Schwartz, Risk Perception law expert Dan Kaham, EPA administrator George Gray, NIOSH Nano Group member David Warheit, and NPR Science Reporter Richard Harris. Registration deadline is October 15, 2007. For more information, go to
http://www.sph.umich.edu/riskcenter/index.htm.

The following MSU Statistics workshops are now accepting registrants: “Intermediate Data Analysis Using SPSS" on October 19, 2007; and “Mixed Model Analysis of Research Data” on November 2, 2007. For detailed information and to register, go to http://www.cstat.msu.edu/.

Experimental Biology 2008 will take place April 5-9, 2008 in San Diego, California. Abstracts are being accepted until November 7, 2007. For more information, go to http://www.eb2008.org/.

This newsletter is produced and distributed weekly by the Center for IntegrativeToxicology. We appreciate suggestions regarding information that might be included in this publication. To be added to the e-mail list, send your name and e-mail address to: Lois Furry, Editor, Center for Integrative Toxicology, Michigan State University, 165C Food Safety and Toxicology Building, East Lansing, MI 48824; furry@msu.edu; 517/353-6469(phone), 517/355-4603(fax).