Toxicology Track

Weekly Newsletter of the MSU Center for Integrative Toxicology
Director: Norbert Kaminski/Editor: Lois Furry

October 30, 2006, Vol. 29, Number 41

Seminars / Publications / Grants / Conferences / Positions

Seminars

The Microbiology and Molecular Genetics Department presents Laura Hale, Duke University, to speak on "Bacterial-Mucosal Interactions in Inflammatory Bowel Disease Pathogenesis" on Tuesday, October 31, 2006 at 4:10 p.m. in 1415 Biomedical Physical Sciences.

*The Pharmacology and Toxicology Department presents Gary Gudelsky, 2006 Distinguished Alumnus, and Chair, Division of Pharmaceutical Sciences at the University of Cincinnati, to speak on "The Agony and Ecstasy: Neuropharmacology of the Methamphetamine Analogue MDMA" on Wednesday, November 1, 2006 at 12 noon in B448-49 Life Sciences.

The Chemistry Department presents Sidney M. Hecht and John W. Mallet, University of Virginia, to speak on "Protein Synthesis Using Tandemly Activated tRNAs" on Wednesday, November 1, 2006 at 4:10 p.m. in 138 Chemistry.

The Neuroscience Department presents Catherine Krull, University of Michigan, to speak on "Axon Guidance in the Periphery" on Thursday, November 2, 2006 at 12:15 p.m. in 1425 Biomedical Physical Sciences.

*The Chemistry Department presents Sidney M. Hecht and John W. Mallet, University of Virginia, to speak on "Anti-tumor Drug Discovery Using Natural Products and Novel Targets" on Thursday, November 2, 2006 at 4:10 p.m. in 138 Chemistry.

The Chemistry Department presents Sidney M. Hecht and John W. Mallet, University of Virginia, to speak on "Bleomycin Mechanisms of Action: Lessons from a Combinatorial Library" on Friday, November 3, 2006 at 4:10 p.m. in 138 Chemistry.

*Fulfills seminar requirements for the Environmental and Integrative Toxicological Sciences Graduate Programs.  Seminars that fulfill this requirement are archived at seminars.

Publications

The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients. Adams TB, McGowen MM, Williams MC, Cohen SM, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Smith RL, Waddell WJ. Food Chem Toxicol. 2006 Aug 30; [Epub ahead of print].

Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype. Irwin R, Lapres JJ, Kinser S, McCabe LR. J Cell Biochem. 2006 Oct 9; [Epub ahead of print].

Growth Trajectories of Extremely Low Birth Weight Infants From Birth to Young Adulthood: A Longitudinal, Population-Based Study. Saigal S, Stoskopf B, Streiner D, Paneth N, Pinelli J, Boyle M. Pediatr Res. 2006 Oct 25; [Epub ahead of print].

Motor and cognitive outcomes in nondisabled low-birth-weight adolescents: early determinants. Whitaker AH, Feldman JF, Lorenz JM, Shen S, McNicholas F, Nieto M, McCulloch D, Pinto-Martin JA, Paneth N. Arch Pediatr Adolesc Med. 2006 Oct;160(10):1040-6.

MFI Zeolite with Small and Uniform Intracrystal Mesopores. Wang H, Pinnavaia TJ. Angew Chem Int Ed Engl. 2006 Oct 17; [Epub ahead of print].

The bacterial species definition in the genomic era.  Konstantinidis KT, Ramette A, Tiedje JM. Philos Trans R Soc Lond B Biol Sci. 2006 Nov 29;361(1475):1929-40.

Extravascular sources of lung angiotensin peptide synthesis in idiopathic pulmonary fibrosis. Li X, Molina-Molina M, Abdul-Hafez A, Ramirez J, Serrano-Mollar A, Xaubet A, Uhal BD. Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L887-95.

Grants

John B. Kaneene, Scott D. Fitzgerald, Steven R. Bolin, Carole Ann Bolin, and Amanda E. Fine received $161,533 from the U.S. Department of Agriculture for "Bovine Tuberculosis: Epidemiology; Diagnosis; and Pathogenesis."

John B. Kaneene, Daniel L. Grooms, Steven R. Bolin, Carole Ann Bolin, and Christopher A. Wolfe received $94,020 and an additional $24,000 from the U.S. Department of Agriculture for "Michigan Johnes Diseases Control Program."

Kaneene also received $14,000 from the Michigan Department of Agriculture for "Evaluating Knowledge Base of Cattle Producers in Michigan Regarding Foreign Animal Diseases and Emergency Management."

James Tiedje and Konstantinow Konstantinidis received $217,482 from the National Science Foundation for "Genomic Approaches to Advance the Species Definition of Prokaryotes."

Jack Harkema and James Wagner received $108,874 from the University of Alabama for "Nasal Injury in Infant Monkeys Exposed to Ozone: Project 3 of a Program Project."

Conferences

The Michigan Regional Chapter of the Society of Toxicology Fall Meeting will be held in East Lansing at the MSU Kellogg Center on Friday November 3, 2006.  The theme is "Endocrine Toxicology."  As in past years, there will be a poster competition that will be judged in three categories:  Graduate Student, Postdoctoral Fellow and Research Associate.  Cash prizes for the best poster will be awarded.  For the registration form and agenda, go to http://www.toxicology.org/isot/rc/michigan/misot.html.

The Developmental and Reproductive Toxicology Committee of the International Life Sciences Institute's Health and Environmental Sciences Institute (HESI) is sponsoring a two-day workshop to foster improvements in alternative models of developmental toxicity.   Breakout groups will cover stem cells, whole embryo culture, zebrafish, and the statistical methods used to turn short-term or in vitro observations into predictions of mammalian developmental toxicity.  Posters are encouraged.  The workshop will be held Feb 27-28, 2007, at the Umstead Hotel, in Raleigh (Cary), North Carolina, USA.   For further information, contact Ms. Regina Graham at HESI (rgraham@hesiglobal.org), or visit the Workshop web page at: http://www.hesiglobal.org/.

Positions

The International Life Sciences Institute (ILSI) is seeking an Executive Director of the Health and Environmental Sciences Institute (HESI) Branch in Washington, D.C. The position requires a minimum of 10-15 years experience at the senior scientific level, having oversight responsibilities for both programmatic and managerial activities.  A Ph.D. or comparable degree in a relevant scientific discipline (i.e., toxicology, pharmacology, public health, etc.) is required.  The incumbent should have demonstrated problem-solving skills that cut across industry, government, and/or academia, with some industry experience preferred.  Among the desired qualities is the ability to facilitate collaboration with academicians, industry representatives, government agencies, volunteer organizations, and other individuals.  A proven track record in public speaking and fund raising will also be an important aspect of the position requirements.  For more information contact the HESI by email: hesi@hesiglobal.org; phone: 202-659-3306; fax: 202-659-3617; or  mail: One Thomas Circle, NW, 9th Floor, Washington, DC 20005-5802.  For more information visit the web site at: http://www.hesiglobal.org/.

The Boeing Company has an opening for an industrial toxicology intern.  A graduate level student in toxicology or industrial hygiene is preferred, but an outstanding undergraduate could be considered.  Must have a strong background in industrial hygiene, toxicology, chemistry, computers and demonstrated ability to solve problems.  Intern will work on one or more projects with opportunities to lead and to team with professionals in Safety, Health and Environmental fields.  Intern will be mentored and coached, and will have an outstanding opportunity to network and learn about aerospace operations.  For more information, go to http://www.boeing.com/employment/college/index.html. Click on intern and grads job search tab and reference requisition number 06-1022874.  All interested applicants must submit resumes on-line. Application deadline is Nov. 30, 2006.